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1. Analyze the major classes of antibiotics and their pharmacokinetic characteristics.
2. Apply current evidenced-based approaches to select appropriate treatment regimens for common infections encountered in clinical practice.
3. Prescribe antimicrobials based on empiric dosing recommendations.
4. Plan goals of therapy and parameters for monitoring therapeutic response to antimicrobials.
5. Recommend specific antimicrobial therapeutic drug monitoring to maximize efficacy and minimize toxicities (e.g., vancomycin and aminoglycosides).
6. Develop preventative strategies to limit antimicrobial resistance.
7. Design patient and caregiver education on the proper use of antimicrobials.

• Antimicrobials
  • Drug classes
  • Pharmacokinetic Properties
    • Concentration-dependent killing
    • Time-dependent killing
    • Post-antibiotic effect
  • Common interactions with other drugs
• Antibacterial Allergies - Sulfa and Penicillin
  • Define true allergy
  • Sulfonamide antibiotics vs non-antibiotics
  • Penicillin - Cephalosporin cross-sensitivity
• Bacteria
  • Differentiation
  • Normal flora
  • Common pathogens
• Antibacterial Resistance - Contributing Factors
  • Trends
  • Mechanisms of resistance
  • Contributing factors
• Methicillin-Resistant Staphylococcus Aureus - Community versus Hospital Acquired
  • Differentiating between CA- and HA-MRSA
  • Current clinical practice guidelines
  • Pharmacologic management
• Enterobacteriaceae Resistance
  • Extended Spectrum Beta-Lactamase (ESBL)
    • What are ESBLs
    • Pharmacologic management
  • Carbapenem-Resistant Enterobacteriaceae (CRE)
    • What are CREs
    • Pharmacologic management
• Urinary Tract Infections
  • Bacterial Etiology, Signs and Symptoms and Diagnosis
  • Cystitis and pyelonephritis
  • Complicated and uncomplicated
  • UTIs in pregnancy
  • Treatment (IDSA Guideline Treatment Algorithm)
    • Acute
    • Recurrent and relapse
• Clostridium Difficile Infection
  • Risk factors
  • Pharmacology management
  • Fecal Transplantation
  • Probiotics literature review
• Community–Acquired Pneumonia
  • Bacterial etiology
  • Diagnosis
  • Typical vs. atypical
  • Treatment (IDSA/ATS Guidelines) and monitoring
    • Outpatient vs. inpatient
    • Empiric treatment
• Healthcare–Associated Pneumonia
  • Bacterial etiology
  • Treatment (IDSA/ATS Guidelines)
  • Treatment Controversy
• Upper Respiratory Tract Infections
  • Sinusitis and pharyngitis
    • Etiology (Viral vs. Bacterial)
    • Treatment
  • Bronchitis and Pertussis
    • Etiology (Viral vs. Bacterial)
    • Treatment
• Skin and Soft Tissue Infections
  • Cellulitis
  • Diabetic foot infections
  • Bacterial etiology
    • Signs & symptoms
    • Treatment (IDSA Guidelines)
  • Osteomyelitis
    • Acute vs. Chronic
    • Oral considerations
• Strategies to Improve Patient Adherence
  • IMS Model (Information-Motivation-Strategy)
  • Major predictors of poor adherence to medication
• Antibacterial Resistance – Prevention Strategies
  • Mechanisms for drug resistance
  • 12 steps to prevent antimicrobial resistance (CDC)
  • Antibiotic stewardship
• Emerging and Reemerging Viral Infections
  • Animals as sources
  • Drivers and ecological factors
  • Modes of transmission
  • Pharmacology management
• Influenza
  • Clinical features
  • Diagnosis
  • Pharmacology management
• Immunizations (Adult)
  • Types of Vaccines
  • General recommendations
  • Contraindications & precautions

Jason Cota, PharmD, MS, is an associate professor and the vice chair of the pharmacy practice department at the University of the Incarnate Word Feik School of Pharmacy. He has over 10 years of experience practicing as an infectious diseases clinical pharmacist at the San Antonio Military Medical Center, where he is a credentialed provider with prescriptive authority.

Dr. Cota completed a two-year Specialty Practice Residency in Pharmacotherapy at The University of Texas Health Science Center at San Antonio with an emphasis in both infectious diseases and nephrology. He is a member of the Society of Infectious Diseases Pharmacists and has given several presentations at national and international meetings. His research has focused on antimicrobial and antifungal drug dosing in patient populations that are subject to altered pharmacokinetics.

Speaker Disclosures:

Financial: Jason Cota is vice chair and associate professor at the University of the Incarnate Word Feik School of Pharmacy. He receives a speaking honorarium from Merck. Dr. Cota receives a speaking honorarium for PESI, Inc.

Non-financial: Jason Cota is a member of the Society of Infectious Diseases Pharmacists.

Save time and $10 off the price of other submission methods – purchase & take the CE test online for $9.99 USD per participant. Additional processing fees apply for other submission methods (i.e. mail, fax, etc.). Please contact our Customer Service at 1-800-844-8260 for more details.

Listed below are the continuing education credit(s) currently available for this non-interactive self-study package. Please note, your state licensing board dictates whether self study is an acceptable form of continuing education. Please refer to your state rules and regulations.

Certificates of Successful Completion are available for email, download and/or printing from your online account immediately following the successful completion of the post-test/evaluation.

**Materials that are included in this course may include interventions and modalities that are beyond the authorized practice of mental health professionals. As a licensed professional, you are responsible for reviewing the scope of practice, including activities that are defined in law as beyond the boundaries of practice in accordance with and in compliance with your professions standards.

All members of the PESI, Inc. planning committee have provided disclosures of financial relationships with ineligible organizations and any relevant non-financial relationships prior to planning content for this activity. None of the committee members had relevant financial relationships with ineligible companies or other potentially biasing relationships to disclose to learners. For speaker disclosures, please see the faculty biography.

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Nurses/Nurse Practitioners/Clinical Nurse Specialists - Credit Expired: 10/24/2021
No CE available for this board.

California Nurses: PESI, Inc. is a provider approved by the California Board of Registered Nursing, Provider #:17118 for 6.0 self-study contact hours.

You will need to provide your license number to PESI. PESI must have this number on file in order for your hours to be valid.

Florida Nurses: PESI, Inc. is an approved provider by the Florida Board of Nursing. Provider #: FBN2858. These materials qualify for 6.0 self-study contact hours.

Iowa Nurses: PESI, Inc. is an approved provider by the Iowa Board of Nursing. Provider #: 346. Nurses successfully completing these self-study materials will earn 6.3 self-study contact hours.

Copies of the evaluation may be sent to the IBON. You will need to provide your license number to PESI. PESI must have this number on file in order for your hours to be valid.

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Pharmacology Nurse Practitioners
This self-study program offers 380 instructional minutes of pharmacology content which is designed to qualify for 6.0 contact hours toward your pharmacology requirement.

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Other Professions
This self-study activity qualifies for 6.25 clock hours of instructional content as required by many national, state and local licensing boards and professional organizations. Retain your certificate of completion and contact your board or organization for specific filing requirements.

Disclaimer: **Information obtained in this course should be used within your scope of practice.
**It is your ethical responsibility to report accurate hours to your licensing board.
**All self-study participants must complete and pass (80% or better) a post-test and evaluation prior to receiving a certificate of completion. If you require a copy of the test/evaluation for CE purposes, please print at the time you take the test. Or you may call our customer service department and a copy of your test/evaluation will be emailed to you. Please allow 30-45 days.

Nurses, Advanced Practice Nurses, Clinical Nurse Specialists, Pharmacists, Nurse Practitioners, Physician Assistants